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 | Acesso ao texto completo restrito à biblioteca da Biblioteca Rui Tendinha. Para informações adicionais entre em contato com biblioteca@incaper.es.gov.br. |
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Registro Completo |
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Biblioteca(s): |
Biblioteca Rui Tendinha. |
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Data corrente: |
29/12/2014 |
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Data da última atualização: |
01/09/2015 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
BRASIL, G. A.; RONCHI, S. N.; NASCIMENTO, A. M.; LIMA, E. M. de.; ROMÃO, W.; COSTA, H. B. da.; SCHERER, R.; VENTURA, J. A.; LENZ, D.; BISSOLI, N. S.; ENDRINGER, D. C.; ANDRADE, T. U. de. |
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Afiliação: |
Girlandia Alexandre Brasil; Silas Nascimento Ronchi; Andrews Marques do Nascimento; Ewelyne Miranda de Lima; Wanderson Romão; Helber Barcellos da Costa; Rodrigo Scherer; Jose Aires Ventura, Incaper; Dominik Lenz; Nazaré Souza Bissoli; Denise Coutinho Endringer; Tadeu Uggere de Andrade. |
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Título: |
Antihypertensive Effect of Carica papaya Via a Reduction in ACE Activity and Improved Baroreflex. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
American Journal of Plant Sciences, 5, 2148-2153. 2014. |
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Descrição Física: |
Planta Med. 2014 Nov ;80(17):1580-7. |
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DOI: |
10.1055/s-0034-1383122 |
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Idioma: |
Inglês |
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Conteúdo: |
The aims of this study were to evaluate the antihypertensive effects of the standardised methanolic extract of Carica papaya, its angiotensin converting enzyme inhibitory effects in vivo, its effect on the baroreflex and serum angiotensin converting enzyme activity, and its chemical composition. The chemical composition of the methanolic extract of C. papaya was evaluated by liquid chromatography-mass/mass and mass/mass spectrometry. The angiotensin converting enzyme inhibitory effect was evaluated in vivo by Ang I administration. The antihypertensive assay was performed in spontaneously hypertensive rats and Wistar rats that were treated with enalapril (10 mg/kg), the methanolic extract of C. papaya (100 mg/kg; twice a day), or vehicle for 30 days. The baroreflex was evaluated through the use of sodium nitroprusside and phenylephrine. Angiotensin converting enzyme activity was measured by ELISA, and cardiac hypertrophy was evaluated by morphometric analysis. The methanolic extract of C. papaya was standardised in ferulic acid (203.41 ± 0.02 µg/g), caffeic acid (172.60 ± 0.02 µg/g), gallic acid (145.70 ± 0.02 µg/g), and quercetin (47.11 ± 0.03 µg/g). The flavonoids quercetin, rutin, nicotiflorin, clitorin, and manghaslin were identified in a fraction of the extract. The methanolic extract of C. papaya elicited angiotensin converting enzyme inhibitory activity. The antihypertensive effects elicited by the methanolic extract of C. papaya were similar to those of enalapril, and the baroreflex sensitivity was normalised in treated spontaneously hypertensive rats. Plasma angiotensin converting enzyme activity and cardiac hypertrophy were also reduced to levels comparable to the enalapril-treated group. These results may be associated with the chemical composition of the methanolic extract of C. papaya, and are the first step into the development of a new phytotherapic product which could be used in the treatment of hypertension. MenosThe aims of this study were to evaluate the antihypertensive effects of the standardised methanolic extract of Carica papaya, its angiotensin converting enzyme inhibitory effects in vivo, its effect on the baroreflex and serum angiotensin converting enzyme activity, and its chemical composition. The chemical composition of the methanolic extract of C. papaya was evaluated by liquid chromatography-mass/mass and mass/mass spectrometry. The angiotensin converting enzyme inhibitory effect was evaluated in vivo by Ang I administration. The antihypertensive assay was performed in spontaneously hypertensive rats and Wistar rats that were treated with enalapril (10 mg/kg), the methanolic extract of C. papaya (100 mg/kg; twice a day), or vehicle for 30 days. The baroreflex was evaluated through the use of sodium nitroprusside and phenylephrine. Angiotensin converting enzyme activity was measured by ELISA, and cardiac hypertrophy was evaluated by morphometric analysis. The methanolic extract of C. papaya was standardised in ferulic acid (203.41 ± 0.02 µg/g), caffeic acid (172.60 ± 0.02 µg/g), gallic acid (145.70 ± 0.02 µg/g), and quercetin (47.11 ± 0.03 µg/g). The flavonoids quercetin, rutin, nicotiflorin, clitorin, and manghaslin were identified in a fraction of the extract. The methanolic extract of C. papaya elicited angiotensin converting enzyme inhibitory activity. The antihypertensive effects eli... Mostrar Tudo |
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Palavras-Chave: |
Carica papaya; Mamão; Rubi INCAPER 511. |
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Thesaurus NAL: |
Antihypertensive; Hypertension. |
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Categoria do assunto: |
Q Segurança Alimentar |
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Marc: |
LEADER 03032naa a2200337 a 4500
001 1004730
005 2015-09-01
008 2014 bl uuuu u00u1 u #d
024 7 $a10.1055/s-0034-1383122$2DOI
100 1 $aBRASIL, G. A.
245 $aAntihypertensive Effect of Carica papaya Via a Reduction in ACE Activity and Improved Baroreflex.$h[electronic resource]
260 $c2014
300 $cPlanta Med. 2014 Nov ;80(17):1580-7.
520 $aThe aims of this study were to evaluate the antihypertensive effects of the standardised methanolic extract of Carica papaya, its angiotensin converting enzyme inhibitory effects in vivo, its effect on the baroreflex and serum angiotensin converting enzyme activity, and its chemical composition. The chemical composition of the methanolic extract of C. papaya was evaluated by liquid chromatography-mass/mass and mass/mass spectrometry. The angiotensin converting enzyme inhibitory effect was evaluated in vivo by Ang I administration. The antihypertensive assay was performed in spontaneously hypertensive rats and Wistar rats that were treated with enalapril (10 mg/kg), the methanolic extract of C. papaya (100 mg/kg; twice a day), or vehicle for 30 days. The baroreflex was evaluated through the use of sodium nitroprusside and phenylephrine. Angiotensin converting enzyme activity was measured by ELISA, and cardiac hypertrophy was evaluated by morphometric analysis. The methanolic extract of C. papaya was standardised in ferulic acid (203.41 ± 0.02 µg/g), caffeic acid (172.60 ± 0.02 µg/g), gallic acid (145.70 ± 0.02 µg/g), and quercetin (47.11 ± 0.03 µg/g). The flavonoids quercetin, rutin, nicotiflorin, clitorin, and manghaslin were identified in a fraction of the extract. The methanolic extract of C. papaya elicited angiotensin converting enzyme inhibitory activity. The antihypertensive effects elicited by the methanolic extract of C. papaya were similar to those of enalapril, and the baroreflex sensitivity was normalised in treated spontaneously hypertensive rats. Plasma angiotensin converting enzyme activity and cardiac hypertrophy were also reduced to levels comparable to the enalapril-treated group. These results may be associated with the chemical composition of the methanolic extract of C. papaya, and are the first step into the development of a new phytotherapic product which could be used in the treatment of hypertension.
650 $aAntihypertensive
650 $aHypertension
653 $aCarica papaya
653 $aMamão
653 $aRubi INCAPER 511
700 1 $aRONCHI, S. N.
700 1 $aNASCIMENTO, A. M.
700 1 $aLIMA, E. M. de.
700 1 $aROMÃO, W.
700 1 $aCOSTA, H. B. da.
700 1 $aSCHERER, R.
700 1 $aVENTURA, J. A.
700 1 $aLENZ, D.
700 1 $aBISSOLI, N. S.
700 1 $aENDRINGER, D. C.
700 1 $aANDRADE, T. U. de.
773 $tAmerican Journal of Plant Sciences, 5, 2148-2153. 2014.
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Registro original: |
Biblioteca Rui Tendinha (BRT) |
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Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
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Registro Completo |
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Biblioteca(s): |
Biblioteca Rui Tendinha. |
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Data corrente: |
20/12/2017 |
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Data da última atualização: |
25/08/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 2 |
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Autoria: |
FORNAZIER, M. J.; MARTINS, D. dos S.; WILLINK, M. C. G. de; PIROVANI, V. D.; FERREIRA, P. S. F.; ZANUNCIO, J. C. |
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Afiliação: |
Mauricio José Fornazier, Incaper; David dos Santos Martins, Incaper; Maria Cristina G. de Willink, Universidad Nacional de Tucumán; Victor D. Pirovani, IFMG; Paulo S. F. Ferreira, UFV; José Cola Zanuncio, UFV. |
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Título: |
Scale insects (Hemiptera: Coccoidea) associated with arabica coffee and geographical distribution in the neotropical region. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Anais da Academia Brasileira de Ciências, v. 89, n. 4, p. 3083-3092. Epub December 11, 2017. |
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Idioma: |
Inglês |
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Conteúdo: |
Coffee is one of the most important Brazilian agricultural commodities exported, and Minas Gerais and Espírito Santo States are the main coffee producers. Scale insects are important coffee pests, and 73 species of Cerococcidae (3), Coccidae (18), Diaspididae (6), Eriococcidae (1), Ortheziidae (3), Pseudococcidae (21), Putoidae (2) and Rhizoecidae (19) have been associated with roots, branches, leaves, flowers and fruits of Arabica coffee in the Neotropics. Eight species were found associated with Arabica coffee in Minas Gerais and Espírito Santo States in this study, and Coccidae was the most frequent family. Coccus alpinus, Cc. celatus, Cc. lizeri, Cc. viridis, and Saissetia coffeae (Coccidae) were found in both states; Alecanochiton marquesi, Pseudaonidia trilobitiformis (Diaspididae), and Dysmicoccus texensis (Pseudococcidae) were only found in Minas Gerais. Alecanochiton marquesi and P. trilobitiformis are first reported in Minas Gerais, and Cc. alpinus in Espírito Santo, on Arabica coffee. All scale insect species were associated with coffee leaves and branches, except D. texensis, associated with coffee roots. Fourty seven scale insect species have been found occurring in Brazilian Arabica coffee, and in Espírito Santo (28) and Minas Gerais (23). Widespread and geographical distribution of each species found are discussed. |
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Palavras-Chave: |
Café arábica. |
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Thesaurus NAL: |
Coccidae; Coffea arabica; Diaspididae; Geographical distribution; Pseudococcidae. |
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Categoria do assunto: |
O Insetos e Entomologia |
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URL: |
https://biblioteca.incaper.es.gov.br/digital/bitstream/123456789/2959/1/BRT-scaleinsectshemipteracoccoidea-fornazier.pdf
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Marc: |
LEADER 02181naa a2200253 a 4500
001 1017635
005 2022-08-25
008 2017 bl uuuu u00u1 u #d
100 1 $aFORNAZIER, M. J.
245 $aScale insects (Hemiptera$bCoccoidea) associated with arabica coffee and geographical distribution in the neotropical region.$h[electronic resource]
260 $c2017
520 $aCoffee is one of the most important Brazilian agricultural commodities exported, and Minas Gerais and Espírito Santo States are the main coffee producers. Scale insects are important coffee pests, and 73 species of Cerococcidae (3), Coccidae (18), Diaspididae (6), Eriococcidae (1), Ortheziidae (3), Pseudococcidae (21), Putoidae (2) and Rhizoecidae (19) have been associated with roots, branches, leaves, flowers and fruits of Arabica coffee in the Neotropics. Eight species were found associated with Arabica coffee in Minas Gerais and Espírito Santo States in this study, and Coccidae was the most frequent family. Coccus alpinus, Cc. celatus, Cc. lizeri, Cc. viridis, and Saissetia coffeae (Coccidae) were found in both states; Alecanochiton marquesi, Pseudaonidia trilobitiformis (Diaspididae), and Dysmicoccus texensis (Pseudococcidae) were only found in Minas Gerais. Alecanochiton marquesi and P. trilobitiformis are first reported in Minas Gerais, and Cc. alpinus in Espírito Santo, on Arabica coffee. All scale insect species were associated with coffee leaves and branches, except D. texensis, associated with coffee roots. Fourty seven scale insect species have been found occurring in Brazilian Arabica coffee, and in Espírito Santo (28) and Minas Gerais (23). Widespread and geographical distribution of each species found are discussed.
650 $aCoccidae
650 $aCoffea arabica
650 $aDiaspididae
650 $aGeographical distribution
650 $aPseudococcidae
653 $aCafé arábica
700 1 $aMARTINS, D. dos S.
700 1 $aWILLINK, M. C. G. de
700 1 $aPIROVANI, V. D.
700 1 $aFERREIRA, P. S. F.
700 1 $aZANUNCIO, J. C.
773 $tAnais da Academia Brasileira de Ciências$gv. 89, n. 4, p. 3083-3092. Epub December 11, 2017.
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Biblioteca Rui Tendinha (BRT) |
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